Improving Compound Quality: Physical Chemistry and DMPK Properties in Drug Discovery.
October 21-24, 2012, Oegstgeest, The Netherlands
Registration Deadline: September 14, 2012
In modern drug discovery, it is important that the Medicinal Chemist understands how to balance potency and ADME properties in order to provide high quality compounds for progression to clinical studies.
This short course will be a mixture of talks and worked exercises designed to further the understanding of DMPK. The course will include: Outlines of the key DMPK in vitro assays: physicochemistry for ADME; Oral drug absorption; Fundamentals of drug distribution; drug metabolizing enzymes; drug transport proteins; basic PK principles and human PK prediction; PKPD relationships.
Contact:
Symposium Secretariat
LD Organisation
Tel : +32 10 45 47 77
Fax : +32 10 45 97 19
e-mail:
More information:
http://www.ldorganisation.com/antfichiers/13382744446th_Short_Course_-_course_outline.pdf
David Spichiger, SCS
11.09.2012